Antioxidant and Redox Regulation of Genes

Lester Packer , Chandan K. Sen , P.A. Baeuerle

This volume addresses oxidant-reduction or redox and antioxidant sensitive molecular mechanisms and how they are implicated in different disease processes. Possible strategies to pharmacologically and/or nutritionally manipulate such redox-sensitive molecular responses are emphasized. It covers - reactive species as intracellular messengers; redox regulation of cellular responses; and, clinical implications of redox signaling and antioxidant therapy.
  • Limba : Engleza
  • Cuprins : Reactive Species as Intracellular Messengers: L.-O. Klotz, K. Briviba, and H. Sies, Signalling by Singlet Oxygen in Biological Systems. D.R. Crawford, T. Suzuki, and K.J.A. Davies, Oxidant-modulated Gene Expression. H.H. Hassanain and P.J. Goldschmidt-Clermont, RAC, Superoxide, and Signal Transduction. S.K. Koliwad, A.K. Brzezinska, and S.J. Elliott, Redox Regulation of Ion Channels. J. Giron-Calle and H.J. Forman, Cell Ca2+ in Signal Transduction: Modulation in Oxidative Stress. G.L. Schieven, Introduction of Protein Tyrosine Phosphorylation by Oxidative Stress and its Implications. A.A. Deora and H.M. Lander, Regulation of Signal Transduction and Gene Expression by Reactive Nitrogen Species. Redox Sensitive Molecular Processes and Cellular Responses: P.A. Baeuerle, Reactive Oxygen Species as Costimulatory Signals of Cytokine-Induced NFkappaB Activation Pathways. T. Okamoto, T. Tetsuka, and T. Kawabe, Redox Regulation of Nuclear Factor kappa B. C.K. Sen, Oxidants and Antioxidants in Aptosis: Role of Bcl-2. V
  • Data Publicarii : 08 Nov 1999
  • Format : Hardback
  • Numar pagini : 562
  • ISBN : 9780126366709
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