Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology. The contents include: clonal evolution of the metastasis phenotype; cell cycle regulation; Apoptosis in tumour growth and metastasis; Angiogenesis in cancer; Cell surface glycoproteins and their receptors; Proteinases and their inhibitors in cancer invasion; Oncogenes and cancer metastasis; Developmental genes; and, Tumour suppressor genes. The contents also include Metastasis suppressor genes and Dominant metastasis-associated genes.
- Limba : Engleza
- Cuprins : Preface. Acknowledgement. Introduction. Clonal Evolution of Metastasis. Inefficiency of the Metastatic Process. Tumor Growth and Metastatic Potential. Cell Cycle Regulation and Metastasis. Apoptosis in Tumor Growth and Metastasis. Angiogenesis in Cancer. Cell Surface Glycoproteins and Their Receptors. Proteinases and Their Inhibitors in Cancer Invasion. Oncogenes and Cancer Metastasis. Developmental Genes and Their Putative Tumor Suppressor Function. Tumor Suppressor Genes. Metastasis Suppressor Genes. Dominant Metastasis Associated Genes. Epilogue. References.
- Data Publicarii : 22 Jun 1997
- Format : Hardback
- Numar pagini : 338
- ISBN : 9780126398755